Synthesis of novel chiral quaternary phosphonium salts with a multiple hydrogen-bonding site, and their application to asymmetric phase-transfer alkylation
作者: Kei Manabe
作者单位: 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
刊名: Tetrahedron, 1998, Vol.54 (48), pp.14465-14476
来源数据库: Elsevier Journal
DOI: 10.1016/S0040-4020(98)00899-0
关键词: asymmetric reactionshydrogen bondingphase transferphosphonium salts
原始语种摘要: Abstract(#br)Chiral phosphonium salts having two NH and two OH groups as hydrogen-bond donors have been synthesized as novel phase-transfer catalysts, and used for asymmetric alkylation of β-keto esters to give the corresponding products with up to 50% ee.
全文获取路径: Elsevier  (合作)
影响因子:2.803 (2012)

  • asymmetric 不对称的
  • alkylation 烷基化
  • phosphonium 膦根
  • hydrogen 
  • salts 盐类
  • chiral 手性的
  • phase 相位
  • esters 酯类
  • quaternary 第四期
  • bonding 焊接