Clinical and Pathological Characterization of Mesoamerican Nephropathy: A New Kidney Disease in Central America
作者: Julia WijkströmRicardo LeivaCarl-Gustaf ElinderSilvia LeivaZulma TrujilloLuis TrujilloMagnus SöderbergKjell HultenbyAnnika Wernerson
作者单位: 1Division of Renal Medicine, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
2Servicio de Nefrologia, Hospital Nacional Rosales, San Salvador, El Salvador
3Department of Evidence based Medicine, Stockholm County Council, Stockholm, Sweden
4Global Safety Assessment, AstraZeneca, Mölndal, Sweden
5Clinical Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden
6Division of CRC, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
刊名: American Journal of Kidney Diseases, 2013, Vol.62 (5), pp.908-918
来源数据库: Elsevier Journal
DOI: 10.1053/j.ajkd.2013.05.019
关键词: Chronic kidney diseaseCentral Americasugarcanerenal pathologyoccupational and environmental healthEl SalvadorMesoamerican nephropathy
原始语种摘要: Background(#br)An endemic of chronic kidney disease (CKD) of unknown cause among rural inhabitants in Central America has been identified. Young and otherwise healthy men working in plantations are frequently affected. The name Mesoamerican nephropathy (MeN) has been suggested. Clinically, MeN presents with low-grade proteinuria and progressive kidney failure. The renal pathology of this disease has not yet been described.(#br)Study Design(#br)Case series.(#br)Setting & Participants(#br)8 male patients with CKD of unknown cause and clinically suspected MeN were recruited from a nephrology unit in El Salvador. All recruited patients had been working on plantations. Kidney biopsies, blood, and urine samples were collected.(#br)Outcomes & Measurements(#br)Renal morphology examined with light...
全文获取路径: Elsevier  (合作)
影响因子:5.294 (2012)

  • 蛋白尿 肾的
  • tubular 管状的
  • glomerular 肾小球病
  • nephropathy 肾病
  • renal 肾的
  • proteinuria 肾的
  • nephrology 肾病学
  • kidney 肾脏
  • interstitial 间隙原子
  • albuminuria 蛋白尿
  • occupational 职业的