A role for adenosine in modulating cardio-respiratory responses: a mini-review
作者: K.M SpyerT Thomas
作者单位: 1Royal Free Campus, Royal Free and University College Medical School, London, UK
刊名: Brain Research Bulletin, 2000, Vol.53 (1), pp.121-124
来源数据库: Elsevier Journal
DOI: 10.1016/S0361-9230(00)00316-6
关键词: Purine nucleotidesAdenosineCardio-respiratoryMedullaNucleus tractus solitarius
原始语种摘要: Abstract(#br)Evidence is provided that purine nucleotides play a major role in modulating cardio-respiratory control through actions at specific sites in the central nervous system (CNS). The accumulation of adenosine in the extracellular space of the nucleus tractus solitarius (NTS) on hypothalamic defence area stimulation is described, and is shown to result from the extracellular breakdown of neurally released adenosine triphosphate (ATP). The actions of adenosine in modulating synaptic actions in the NTS are discussed in relation to the potential presynaptic action of adenosine in modulating transmitter release. Actions of adenosine and ATP at other sites in the medulla concerned with cardio-respiratory control are discussed. The inter-relationships between ATP and adenosine are...
全文获取路径: Elsevier  (合作)
影响因子:2.935 (2012)

  • adenosine 腺苷
  • respiratory 呼吸过程
  • modulating 调制的
  • cardio 
  • actions 对策
  • stimulation 激励
  • tractus 
  • triphosphate 三磷酸盐
  • central 中心的
  • breakdown 故障