Perinatal changes of brain-derived neurotrophic factor in pre- and fullterm neonates
作者: Ariadne Malamitsi-PuchnerEmmanuel EconomouOurania RigopoulouTheodora Boutsikou
作者单位: 1Neonatal Division, 2nd Department of Obstetrics and Gynecology, University of Athens, 19, Soultani str., GR-10682 Athens, Greece
刊名: Early Human Development, 2003, Vol.76 (1), pp.17-22
来源数据库: Elsevier Journal
DOI: 10.1016/j.earlhumdev.2003.10.002
关键词: Brain-derived neurotrophic factorPerinatal periodPreterm neonateFullterm ineonate
原始语种摘要: Abstract(#br)Background : Brain-derived neurotrophic factor (BDNF) is abundant in brain and peripheral nerves, affects normal development, growth and survival and is implicated in immune response. Aim : To determine in single preterm (P) and fullterm (F) neonates, circulating intra- and extrauterine levels of BDNF, supposingly reflecting their neuronal and immune maturity. Study design : Prospective study. Subjects : Thirty healthy, appropriate for gestational age (AGA) F (mean gestational age 39.2±1.4 weeks), 15 healthy AGA P (29.4±1.3 weeks), and their mothers. Outcome measures : BDNF was measured by enzyme immunoassay methods in the serum of: mothers at the first stage of labor (MS), the umbilical cord (UC) and the neonates on days 1 (N1) and 4 (N4) postpartum. Results : Levels of BDNF...
全文获取路径: Elsevier  (合作)
影响因子:2.02 (2012)

  • neurotrophic 神经营养的
  • derived 导生的
  • immune 免疫的
  • factor 因素
  • stimulation 激励
  • gestational 妊娠期的
  • extrauterine 子宫外的
  • neonate 新生儿
  • antigenic 抗原的
  • mature 成孰的