Preventive Effects of Vitamin E Against Oxidative Damage in Aged Diabetic Rat Bladders
作者: Hülya AybekZafer AybekGülçin AbbanSimin Rota
作者单位: 1Department of Biochemistry, Faculty of Medicine, Pamukkale University, Denizli, Turkey
2Department of Urology, Faculty of Medicine, Pamukkale University, Denizli, Turkey
3Department of Histology and Embriyology, Faculty of Medicine, Pamukkale University, Denizli, Turkey
刊名: Urology, 2010, Vol.77 (2), pp.508.e10-508.e14
来源数据库: Elsevier Journal
DOI: 10.1016/j.urology.2010.08.015
原始语种摘要: Objectives(#br)To examine the effects of aging and/or diabetes mellitus on oxidative stress and the protective effect of vitamin E in the bladder. It was proposed that the balance between oxidant and antioxidant species is important regarding the aging process and prevention of diabetic complications.(#br)Methods(#br)Young and aged rats were randomly allotted into six experimental groups: aged control, aged diabetic, aged diabetic and vitamin E–treated, young control, young diabetic, young diabetic and vitamin E–treated. Diabetes was induced by streptozotocin. Vitamin E was administered to the treated groups. Malondialdehyde and reduced glutathione levels were measured in all rat bladders, and histological changes were examined by electron microscopy.(#br)Results(#br)We found increased...
全文获取路径: Elsevier  (合作)
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影响因子:2.424 (2012)

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关键词翻译
关键词翻译
  • diabetic 糖尿病患者
  • vitamin 维生素
  • streptozotocin 链脲佐菌素
  • glutathione 谷胱甘肽
  • young 年轻的
  • diabetes 糖尿病
  • treated 加工的
  • reduced 减缩的
  • control 控制
  • radical