Synthesis, characterization, and mineralization of polyamide-6/calcium lactate composite nanofibers for bone tissue engineering
作者: Hem Raj PantPrabodh RisalChan Hee ParkLeonard D. TijingYeon Jun JeongCheol Sang Kim
作者单位: 1Department of Bio-nano System Engineering, Chonbuk National University, Jeonju 561-756, Republic of Korea
2Department of Engineering Science and Humanities, Institute of Engineering, Pulchowk Campus, Tribhuvan University, Kathmandu, Nepal
3Department of Surgery, Chonbuk National University Medical School, Jeonju 561-712, Republic of Korea
4Division of Mechanical Design Engineering, Chonbuk National University, Jeonju 561-756, Republic of Korea
刊名: Colloids and Surfaces B: Biointerfaces, 2013, Vol.102 , pp.152-157
来源数据库: Elsevier Journal
DOI: 10.1016/j.colsurfb.2012.08.032
关键词: Polyamide-6Calcium lactateNanofibersBiomaterialsElectrospinning
原始语种摘要: Abstract(#br)Polyamide-6 nanofibers containing calcium lactate (CL) on their surface were prepared by neutralization of lactic acid (LA) in core–shell structured polyamide-6/LA electrospun fibers. First, simple blending of LA with polyamide-6 solution was used for electrospinning which interestingly formed a thin LA layer around polyamide-6 nanofibers (core–shell structure) and then subsequent conversion of this LA into calcium lactate via neutralization using calcium base. FE-SEM and TEM images revealed that plasticizer capacity of LA led the formation of point-bonded structure due to the formation of shell layer of LA and core of polyamide-6. The bone formation ability of polyamide-6/calcium lactate composite fibers was evaluated by incubating in biomimetic simulated body fluid (SBF)....
全文获取路径: Elsevier  (合作)
影响因子:3.554 (2012)

  • polyamide 聚酰胺
  • composite 复合的
  • calcium 
  • lactate 乳酸盐
  • pristine 太古的
  • shell 贝壳
  • formation 建造
  • faster 加快
  • deposition 沉积
  • neutralization 中和