The emergence of OXA-48- and NDM-1-positive Klebsiella pneumoniae in Riyadh, Saudi Arabia
作者: Atef ShiblMohamed Al-AgamyZiad MemishAbiola SenokShamshad Abdul KhaderAbdullah Assiri
作者单位: 1College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
2Department of Pathology and Pharmacology, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia
3Preventive Medicine Directorate, Ministry of Health, Riyadh, Saudi Arabia
4King Saud Medical City, Riyadh, Saudi Arabia
刊名: International Journal of Infectious Diseases, 2013, Vol.17 (12), pp.e1130-e1133
来源数据库: Elsevier Journal
DOI: 10.1016/j.ijid.2013.06.016
关键词: Klebsiella pneumoniaeOXA-48NDM-1CarbapenemasesMetallo-beta-lactamasesCarbapenem-hydrolyzing class DSaudi Arabia
原始语种摘要: Summary(#br)Objectives(#br)To investigate the emergence of NDM-, OXA-48-, and VIM-producing Klebsiella pneumoniae in Saudi Arabia.(#br)Methods(#br)From June to December 2011, we obtained K. pneumoniae isolates with reduced sensitivity to carbapenem identified in Riyadh, Saudi Arabia. Only non-duplicate clinical and surveillance isolates obtained from inpatients were included. PCR amplification was carried out for the detection of extended-spectrum beta-lactamase genes ( bla CTX-M , bla TEM , bla SHV ) and carbapenemase genes ( bla KPC , bla VIM , bla IMP , bla NDM , and bla OXA-48 ). Susceptibility to imipenem, meropenem, amikacin, gentamicin, trimethoprim–sulfamethoxazole, and colistin was determined.(#br)Results(#br)Of the 60 K. pneumoniae isolates studied, 45 were...
全文获取路径: Elsevier  (合作)
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影响因子:2.357 (2012)

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关键词翻译
关键词翻译
  • Saudi Arabia 沙特阿拉伯
  • NDM Network Data Mover
  • isolates 单离体
  • colistin 粘菌素
  • hydrolyzing 水解的
  • carbapenem 氨基甲酰
  • gentamicin 艮他霉素
  • amikacin 丁胺卡那霉素
  • trimethoprim 三甲氧苄二氨嘧啶
  • lactamase 内酰胺酶