Lobular phenotype related to occult-metastatic spread in axillary sentinel node and/or bone marrow in breast carcinoma
作者: Anne Vincent-SalomonMartial CalyYann De RyckePaul FréneauxJerzy KlijanienkoMarick LaéFrédérique ViardClaude NosFrançois-Clément BidardSéverine AlranRémy SalmonYoulia KirovaJean-Yves PiergaBrigitte Sigal-ZafraniXavier Sastre-Garau
作者单位: 1Department of Pathology, Institut Curie, 26 rue d’Ulm, 75005 Paris Cedex, France
2Department of Biostatistics, Institut Curie, 26 rue d’Ulm, 75005 Paris Cedex, France
3Department of Surgery, Institut Curie, 26 rue d’Ulm, 75005 Paris Cedex, France
4Department of Medical Oncology, Institut Curie, 26 rue d’Ulm, 75005 Paris Cedex, France
5Department of Radiation Therapy, Institut Curie, 26 rue d’Ulm, 75005 Paris Cedex, France
刊名: European Journal of Cancer, 2009, Vol.45 (11), pp.1979-1986
来源数据库: Elsevier Journal
DOI: 10.1016/j.ejca.2009.03.015
关键词: Lobular carcinomaOccult metastasisSentinel nodeBone marrow micro-metastasisEarly dissemination
原始语种摘要: Abstract(#br)To determine whether any histological trait was associated with regional and/or systemic spread of occult tumour cells (OTCs) in small size invasive breast cancer, we compared tumour characteristics, axillary sentinel lymph node (SN) and bone marrow (BM) status in a series of 287 pT1T2 cases.(#br)Surgery was the first step of treatment, associated with SN procedure and with BM aspiration for the detection of OTC. SN was histologically classified as negative, metastatic (>2mm), micro-metastatic (>0.2mm and ⩽2mm) or involved by OTC detected by immunohistochemistry (Ni+, ⩽0.2mm). BM specimens were analysed after immunocytochemistry and classified as negative or positive with atypical cytokeratin-positive...
全文获取路径: Elsevier  (合作)
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影响因子:5.061 (2012)

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关键词翻译
关键词翻译
  • sentinel 标志
  • axillary 腋生的
  • carcinoma 癌症
  • breast 胸部
  • occult 隐的
  • metastatic 新陈代谢的
  • phenotype 表型
  • metastasis 同质蜕变
  • dissemination 散布
  • marrow 骨髓