Clinical and biological factors associated with recurrences of severe toxoplasmic retinochoroiditis confirmed by aqueous humor analysis
作者: Alexandre MatetLuc ParisChristine FardeauCéline TerradaEmmanuelle ChampionArnaud FekkarNathalie CassouxValérie TouitouPhuc LeHoangBahram Bodaghi
作者单位: 1Ophthalmology Department, Reference Center in Rare diseases, DHU ViewRestore, Pitié-Salpêtrière Hospital, Paris VI University, F-75013 Paris, France
2Parasitology Department, Pitié-Salpêtrière Hospital, Paris VI University, F-75013 Paris, France
刊名: American Journal of Ophthalmology, 2018
来源数据库: Elsevier Journal
DOI: 10.1016/j.ajo.2018.11.013
关键词: ToxoplasmosisRecurrencesAqueous humorNatural historyRisk factorsTime factorsPolymerase chain reactionImmunoblotTreatmentVasculitis
英文摘要: Abstract(#br)Purpose(#br)To investigate clinical and biological factors influencing recurrences of severe toxoplasmic retinochoroiditis (TRC) confirmed by aqueous humor analysis.(#br)Design(#br)Retrospective case series.(#br)Methods(#br)Retrospective analysis of 87 subjects with severe TRC, proven by positive Goldmann-Witmer coefficient (GWC), Toxoplasma gondii ( T.gondii ) immunoblot, or T.gondii -specific polymerase chain reaction (PCR) in aqueous humor. Cases with immunosuppression or retinal scars without previous recorded episode were excluded. Time-dependent, clinical, treatment-related and biological factors were explored by uni- and multivariate shared frailty survival analyses.(#br)Results(#br)Among 44 included subjects (age, 40.4±17.6 years; follow-up, 8.3±2.7 years), 22 cases...
全文获取路径: Elsevier  (合作)
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来源刊物:
影响因子:3.631 (2012)

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关键词翻译
关键词翻译
  • confirmed 已确认的
  • associated 相关的
  • biological 生物学的
  • aqueous 水的
  • humor 体液
  • severe 严滥
  • analysis 分析