The Clinical Presentation, Survival Outcomes, and Management of Patients With Renal Cell Carcinoma and Cardiac Metastasis Without Inferior Vena Cava Involvement: Results From a Pooled Clinical Trial Database and Systematic Review of Reported Cases
作者: Mariuxi A. Viteri MaloneGustavo Ruiz AresGuillermo De VelascoRaphael BrandãoXun LinCraig NortonRonit SimantovJavid MoslehiKatherine M. KrajewskiToni K. ChoueiriRana R. McKay
作者单位: 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
2Pfizer Oncology, New York, NY
3Cardio-Oncology Program, Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University, Nashville, TN
4Department of Medicine, Division of Hematology/Oncology, University of California, San Diego, La Jolla, CA
刊名: Clinical Genitourinary Cancer, 2018, Vol.16 (2), pp.e327-e333
来源数据库: Elsevier Journal
DOI: 10.1016/j.clgc.2017.11.005
关键词: Heart metastasisKidney cancerLeft ventricleRight ventricleTargeted therapy
英文摘要: Abstract(#br)Background(#br)Cardiac metastases from renal cell carcinoma (RCC) are uncommon and there are limited data regarding the presentation and outcomes of this population. The objective of this study was to evaluate the characteristics and outcomes of patients with RCC with cardiac metastasis without inferior vena cava (IVC) involvement.(#br)Materials and Methods(#br)We conducted a pooled retrospective analysis of metastatic RCC patients treated in 4 clinical trials. Additionally, we conducted a systematic review of cases reported in the literature from 1973 to 2015. Patients with cardiac metastases from RCC without IVC involvement were included. Patient and disease characteristics were described. Additionally, treatments, response to therapy, and survival outcomes were...
全文获取路径: Elsevier  (合作)
影响因子:1.429 (2012)