Associations between history of chronic lung disease and non–small cell lung carcinoma in Maryland: variations by sex and race
作者: Lisa D. GardnerChristopher A. Loffredo, PhDPatricia LangenbergDiane Marie St. GeorgeJanaki DeepakCurtis C. HarrisSania Amr
作者单位: 1Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD
2Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC
3Department of Medicine, University of Maryland School of Medicine, Baltimore, MD
4Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
5Marlene and Stuart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD
刊名: Annals of Epidemiology, 2018
来源数据库: Elsevier Journal
DOI: 10.1016/j.annepidem.2018.04.012
关键词: Chronic lung diseaseNon-small cell lung carcinoma (NSCLC)Chronic obstructivePulmonary disease (COPD)AsthmaInflammation
英文摘要: Abstract(#br)Purpose(#br)Lung cancer is a multifactorial malignancy for which some risk factors, such as chronic lung diseases, their interactions with smoking, and how they differ by race and sex, are not fully understood. We investigated the associations between chronic inflammatory lung disease and non–small cell lung carcinoma (NSCLC) and how sex and race may affect such associations.(#br)Methods(#br)Using logistic regression, we analyzed 1660 lung cancer cases and 1959 population controls and estimated adjusted odds ratios (AORs) and 95% confidence intervals (CIs).(#br)Results(#br)Chronic lung disease was significantly associated with higher odds of having NSCLC in never (AOR = 1.99; 95% CI = 1.19–3.34), former (AOR = 1.68; 95% CI = 1.29–2.20), and current smokers (AOR = 2.40; 95% CI...
全文获取路径: Elsevier  (合作)
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影响因子:2.479 (2012)

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关键词翻译
关键词翻译
  • Maryland 马里兰猪种
  • carcinoma 癌症
  • history 历史
  • between 在中间
  • small 小的
  • chronic 延续很长的
  • disease