Somatosympathetic reflex in a working heart-brainstem preparation of the rat
作者: J.T PottsK.M SpyerJ.F.R Paton
作者单位: 1Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA
2Department of Physiology, University College London and Royal Free School of Medicine, London, UK
3University of Bristol, Bristol, UK
刊名: Brain Research Bulletin, 2000, Vol.53 (1), pp.59-67
来源数据库: Elsevier Journal
DOI: 10.1016/S0361-9230(00)00309-9
关键词: Somatosensory afferentsMuscle contractionSpinal/supraspinal sensory pathwaysNucleus of the solitary tractCardiovascular/respiratory regulation
原始语种摘要: Abstract(#br)The purpose of the present study was to examine the cardiorespiratory responses (CR) evoked by a somatosympathetic reflex (SSR) in the working heart-brainstem preparation (WHBP). Sprague–Dawley rats (75–100 g) were anesthetized with halothane, bisected sub-diaphramatically and decerebrated pre-collicularly ( n = 15). The preparation was transferred to a recording chamber and perfused via the thoracic aorta with Ringer’s solution containing an oncotic agent (Ficoll, 1.25%). SSR was activated by electrical stimulation (5 s) of the brachial nerve (0.5–40 Hz, 1–20 V, 0.1 ms) or the forelimb (0.5–40 Hz, 5–60 V, 2 ms). Stimulation at 40 Hz significantly increased heart rate (HR, 366 ± 10 to 374 ± 9 beats/min), systemic perfusion pressure (PP, 83 ± 5 to 89 ± 6 mmHg) and phrenic...
全文获取路径: Elsevier  (合作)
影响因子:2.935 (2012)

  • reflex 反射
  • brainstem 脑干
  • supraspinal 刺突上的
  • heart 心脏
  • stimulation 激励
  • working 开采
  • brachial 臂的
  • forelimb 前翼
  • nerve 叶脉
  • altering 修改