Calorimetric evaluation of the interaction and absorption of eicosapentaenoic acid by biomembrane models
作者: Maria Grazia SarpietroSara OttimoMaria Chiara GiuffridaDorotea MicieliFrancesco Castelli
作者单位: 1Dipartimento di Scienze Chimiche, Università degli Studi di Catania, Viale A. Doria 6, 95125 Catania, Italy
刊名: Thermochimica Acta, 2009, Vol.495 (1), pp.149-154
来源数据库: Elsevier Journal
DOI: 10.1016/j.tca.2009.06.014
关键词: Eicosapentaenoic acidDifferential scanning calorimetryBiomembrane modelsEPA
原始语种摘要: Abstract(#br)The interaction of eicosapentaenoic acid, a polyunsaturated fatty acid belonging to the omega-3 class, with biomembrane models represented by multilamellar or unilamellar vesicles made of dimyristoylphosphatidylcholine was monitored by means of differential scanning calorimetry technique. The calorimetric analysis of vesicle prepared in the presence of increasing molar fraction of eicosapentaenoic acid was carried out to show its maximum interaction with biomembrane models evaluating the effects of eicosapentaenoic acid on the biomembrane models thermotropic parameters (transition temperature and enthalpy variation). Furthermore, in order to detect the influence of the presence of hydrophilic or lipophilic media on the entity of the compound absorption by the biomembrane...
全文获取路径: Elsevier  (合作)
影响因子:1.989 (2012)

  • 奥米加 转移
  • biomembrane 生物膜
  • absorption 吸收
  • interaction 相互酌
  • enthalpy 
  • transition 转移
  • omega 转移
  • variation 变异
  • hydrophilic 亲水的
  • calorimetry 热量测定法
  • thermotropic 正温的