Optimal branched-chain amino acid ratio improve cell proliferation and protein metabolism of porcine enterocytesin vivo and in vitro
作者: Yehui DuanBie TanJianjun LiPeng LiaoBo HuangFengna LiHao XiaoYanhong LiuYulong Yin
作者单位: 1Laboratory of Animal Nutritional Physiology and Metabolic Process, Key Laboratory of Agro-ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, Hunan, China
2Department of Animal Science, University of California, Davis 95616, California, USA
3Laboratory of Animal Nutrition and Human Health, School of Biology, Hunan Normal University, Changsha, Hunan 410018, China
刊名: Nutrition, 2018
来源数据库: Elsevier Journal
DOI: 10.1016/j.nut.2018.03.057
关键词: Branched-chain amino acid ratioCell proliferationProtein metabolismSmall intestinePigs
英文摘要: Abstract(#br)Objectives(#br)The objective of this study was to investigate the effects of different branched-chain amino acids (BCAA) ratios on intestinal cell proliferation and protein metabolism.Methods and Results:The in vivo study was conducted in growing pigs(average initial body weight = 9.85 ± 0.35 kg) exposed to different Leu: Ile: Val ratios (1:1:1, 1:0.75:0.75, 1:0.51:0.63, and 1:0.25:0.25) in 17% CP diets for 45 days to determine intestinal morphology, cell proliferation and AA transporter mRNA expression. The in vitro study was performed in porcine jejunal epithelial cell line to investigate the effects of different BCAA ratios (0, 1:0.25:0.25, 1:0.5:0.5, and 1:1:1) on cell proliferation, AA transporter expression and protein turnover.Results showed that relative to the...
全文获取路径: Elsevier  (合作)
影响因子:2.859 (2012)

  • metabolism 代谢
  • improve 改进
  • branched 分枝的
  • protein 蛋白质
  • chain 
  • porcine 猪的
  • vitro 体外
  • ratio 
  • amino 氨基
  • proliferation 增生