A quantitative study of sodium tungstate protective effect on pancreatic beta cells in streptozotocin-induced diabetic rats
作者: Zahra HeidariHamidreza Mahmoudzadeh-SaghebBita Moudi
作者单位: 1Division of Histology, Faculty of Medicine, Zahedan University of Medical Sciences, P.O. Box 98165-488, Zahedan, Iran
2Sciences & Research Branch of Azad University, Tehran, Iran
刊名: Micron, 2008, Vol.39 (8), pp.1300-1305
来源数据库: Elsevier Journal
DOI: 10.1016/j.micron.2008.02.014
关键词: Diabetes mellitusSodium tungstateStereologyBeta cell
原始语种摘要: Abstract(#br)Diabetes is a major public health problem. Development of new therapies that are able to improve glycemia management, cure diabetes, and can even protect from it, are of great interest. This study investigated the protective effect of sodium tungstate against STZ-induced beta-cell damages by means of stereological methods. Sixty rats were divided into six groups: control (C), tungstate-treated control (TC), STZ-induced diabetic (D), STZ-induced diabetic rats were treated by sodium tungstate from 1 week before STZ injection (TDB), food-restricted diabetic (FRD), and diabetic rats treated with sodium tungstate 1 week after STZ administration (TDA). Stereological estimation of pancreas volume, islets volume density, volume-weighted mean islets volume and mass of beta cells,...
全文获取路径: Elsevier  (合作)
影响因子:1.876 (2012)

  • diabetic 糖尿病患者
  • streptozotocin 链脲佐菌素
  • induced 感应的
  • pancreatic 胰的
  • sodium 
  • tungstate 钨酸盐
  • glycemia 血糖
  • diabetes 糖尿病
  • volume 体积
  • pancreas