Impact of adjuvant therapy on recurrence patterns in stage I uterine carcinosarcoma
作者: Koji MatsuoKohei OmatsuMalcolm S. RossMarian S. JohnsonMayu YunokawaMerieme M. KlobocistaDwight D. ImStephen H. BushYutaka UedaTadao TakanoErin A. BlakeKosei HasegawaTsukasa BabaMasako ShidaShinya SatohTakuhei YokoyamaHiroko MachidaSosuke AdachiYuji IkedaKeita IwasakiTakahito M. MiyakeShiori YanaiMasato NishimuraTadayoshi NaganoMunetaka TakekumaSatoshi TakeuchiTanja PejovicMian MK ShahzadFrederick R. UelandJoseph L. KelleyLynda D. Roman
作者单位: 1Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Southern California, CA, USA
2Department of Gynecology, Cancer Institute Hospital, Tokyo, Japan
3Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh, PA, USA
4Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, KY, USA
5Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan
6Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Albert Einstein College of Medicine, Montefiore Medical Center, NY, USA
7The Gynecologic Oncology Center, Mercy Medical Center, Baltimore, MD, USA
8Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Moffitt Cancer Center, University of South Florida, FL, USA
9Department of Obstetrics and Gynecology, Osaka University, Osaka, Japan
10Department of Obstetrics and Gynecology, Tohoku University, Miyagi, Japan
11Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Colorado, CO, USA
12Department of Obstetrics and Gynecology, Saitama Medical University International Medical Center, Saitama, Japan
13Department of Obstetrics and Gynecology, Kyoto University, Kyoto, Japan
14Department of Obstetrics and Gynecology, Tokai University, Kanagawa, Japan
15Department of Obstetrics and Gynecology, Tottori University, Tottori, Japan
16Department of Obstetrics and Gynecology, Osaka Rosai Hospital, Osaka, Japan
17Department of Obstetrics and Gynecology, Niigata University, Niigata, Japan
18Department of Obstetrics and Gynecology, The University of Tokyo, Tokyo, Japan
19Department of Obstetrics and Gynecology, Aichi Medical University, Aichi, Japan
20Department of Obstetrics and Gynecology, Kawasaki Medical School, Okayama, Japan
21Department of Obstetrics and Gynecology, Kurashiki Medical Center, Okayama, Japan
22Department of Obstetrics and Gynecology, Tokushima University, Tokushima, Japan
23Department of Obstetrics and Gynecology, Kitano Hospital, Osaka, Japan
24Department of Obstetrics and Gynecology, Shizuoka Cancer Center, Shizuoka, Japan
25Department of Obstetrics and Gynecology, Iwate Medical University, Iwate, Japan
26Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Oregon Health & Science University, OR, USA
刊名: Gynecologic Oncology, 2017, Vol.145 (1), pp.78-87
来源数据库: Elsevier Journal
DOI: 10.1016/j.ygyno.2017.02.001
关键词: Uterine carcinosarcomaStage IChemotherapyRadiotherapyRecurrenceSurvival outcome
英文摘要: Abstract(#br)Background(#br)To examine recurrence patterns in women with stage I uterine carcinosarcoma (UCS) stratified by adjuvant therapy pattern.(#br)Methods(#br)We examined 443 cases of stage I UCS derived from a retrospective cohort of 1192 UCS cases from 26 institutions. Adjuvant therapy patterns after primary hysterectomy-based surgery were correlated to recurrence patterns.(#br)Results(#br)The most common adjuvant therapy was chemotherapy alone (41.5%) followed by chemotherapy/radiotherapy (15.8%) and radiotherapy alone (8.4%). Distant-recurrence was the most common recurrence pattern (5-year cumulative rate, 28.1%) followed by local-recurrence (13.3%). On multivariate analysis, chemotherapy but not radiotherapy remained an independent prognostic factor for decreased risk of...
全文获取路径: Elsevier  (合作)
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来源刊物:
影响因子:3.929 (2012)

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关键词翻译
关键词翻译
  • carcinosarcoma 癌肉瘤
  • uterine 子宫的
  • recurrence 循环
  • adjuvant 辅助剂
  • stage 
  • outcome 效果
  • therapy 治疗