Childhood sexual abuse and hypothalamus-pituitary-thyroid axis in postpartum major depression
作者: Anna PlazaLluïsa Garcia-EsteveCarlos AscasoPurificación NavarroEstel GelabertIrene HalperinManuel ValdésRocío Martín-Santos
作者单位: 1Unit of Perinatal Psychiatry and Gender Research, Hospital Clinic Universitari of Barcelona, 08028, Barcelona, Spain
2Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
3Department of Public Health of the University of Barcelona, 08036 Barcelona, Spain
4Neuropsychopharmacology Programe, IMIM-Hospital del Mar, 08003 Barcelona, Spain
5Department of Psychiatry, Neuroscience Institute, Hospital Clínic, University of Barcelona, 08036 Barcelona, Spain
6Department of Endocrinology, Hospital Clínic, University of Barcelona, 08036 Barcelona, Spain
7Centros de Investigación en Red de Salud MEntal (CIBERSAM), Spain
刊名: Journal of Affective Disorders, 2009, Vol.122 (1), pp.159-163
来源数据库: Elsevier Journal
DOI: 10.1016/j.jad.2009.07.021
关键词: Postpartum depressionHypothalamus-pituitary-thyroid axisThyroid dysfunctionAntithyroid autoantibodiesEarly life eventsSexual abuse
原始语种摘要: Abstract(#br)Objective(#br)The aim of this study was to investigate the association between early life events in women with postpartum major depression and concomitant hypothalamus-pituitary-thyroid axis disturbances (HPTD), thyroid dysfunction or presence of thyroid antibodies.(#br)Methods(#br)Serum total tri-iodothyronine (TT3), free thyroxin (FT4), Thyroid-stimulating hormone (TSH), Thyroperoxidasa (TPOAb) and Thyroglobulin (TGAb) autoantibodies was measured in 103 major postpartum depressive women. HPTD was defined as TSH and/or T4 abnormal, presence of thyroid autoantibodies and alterations of TT3. All women were assessed with a psychiatry structured interview for DSM-IV. Early Trauma Inventory Self Report, sociodemographic, reproductive, psychosocial and psychopathological variables...
全文获取路径: Elsevier  (合作)
影响因子:3.295 (2012)

  • abuse 滥用
  • depression 低地
  • pituitary 垂体的
  • postpartum 产后的
  • thyroid 甲状腺
  • hypothalamus 丘脑下部
  • sexual 两性的
  • major 知的
  • depressive 降低的
  • psychiatry 精神病学