Longitudinal in vivo imaging of bone formation and resorption using fluorescence molecular tomography
作者: F.M. LambersF. StukerC. WeigtG. KuhnK. KochF.A. SchulteJ. RipollM. RudinR. Müller
作者单位: 1Institute for Biomechanics, ETH Zürich, Zürich, Switzerland
2Institute for Biomedical Engineering, University and ETH Zürich, Zürich, Switzerland
3Institute of Electronic Structure and Laser, Foundation for Research and Technology-Hellas (FORTH), Heraklion, Crete, Greece
刊名: Bone, 2013, Vol.52 (2), pp.587-595
来源数据库: Elsevier Journal
DOI: 10.1016/j.bone.2012.11.001
关键词: Multimodality imagingFluorescence molecular tomographyIn vivo micro-computed tomographyDynamic bone morphometryBone
原始语种摘要: Abstract(#br)Bone research often focuses on anatomical imaging of the bone microstructure, but in order to gain better understanding in how bone remodeling is modulated through interventions also bone formation and resorption processes should be investigated. With this in mind, the purpose of this study was to establish a longitudinal in vivo imaging approach of bone formation and resorption using fluorescence molecular tomography (FMT). In this study the reproducibility, accuracy and sensitivity of FMT for bone imaging were assessed by performing longitudinal measurements with FMT and comparing it to in vivo micro-computed tomography on a set of control mice, and mice in which load-adaptation was induced in the sixth caudal vertebra. The precision error for FMT measurements, expressed as...
全文获取路径: Elsevier  (合作)
影响因子:3.823 (2012)

  • resorption 再吸收
  • imaging 图像形成
  • tomography 断层x 线摄影
  • formation 建造
  • micro 
  • fluorescence 荧光
  • longitudinal 纵向的
  • indicating 指示
  • measured 量过的
  • vertebra 椎骨