Diurnal variations in iron concentrations and expression of genes involved in iron absorption and metabolism in pigs
作者: Yiming ZhangDan WanXihong ZhouCiming LongXin WuLan LiLiuqin HePan HuangShuai ChenBie TanYulong Yin
作者单位: 1Key Laboratory of Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Changsha, Hunan 410125, China
2Animal Nutrition and Human Health Laboratory, School of Life Sciences, Hunan Normal University, Changsha, Hunan 410125, China
刊名: Biochemical and Biophysical Research Communications, 2017, Vol.490 (4), pp.1210-1214
来源数据库: Elsevier Journal
DOI: 10.1016/j.bbrc.2017.06.187
关键词: IronUp takeHomeostasisDiurnal variationPig
英文摘要: Abstract(#br)Diurnal variations in serum iron levels have been well documented in clinical studies, and serum iron is an important diagnostic index for iron-deficiency anemia. However, the underlying mechanism of dynamic iron regulation in response to the circadian rhythm is still unclear. In this study, we investigated daily variations in iron status in the plasma and liver of pigs. The transcripts encoding key factors involved in iron uptake and homeostasis were evaluated. The results showed that iron levels in the plasma and liver exhibited diurnal rhythms. Diurnal variations were also observed in transcript levels of divalent metal transporter 1 ( DMT1 ), membrane-associated ferric reductase 1 ( DCYTB ), and transferrin receptor ( TfR ) in the duodenum and jejunum, as well as hepcidin...
全文获取路径: Elsevier  (合作)

  • expression 表示
  • involved 涉及
  • absorption 吸收
  • metabolism 代谢
  • concentrations 浓聚物