Differentiation of vascular tumors from vascular malformations by expression of Wilms tumor 1 gene: Evaluation of 126 cases
作者: Rola Al DhaybiJulie PowellCatherine McCuaigVictor Kokta
作者单位: 1Division of Dermatology, Centre Hospitalier Universitaire Sainte-Justine, University of Montreal, Montreal, Quebec, Canada
2Department of Pathology, Centre Hospitalier Universitaire Sainte-Justine, University of Montreal, Montreal, Quebec, Canada
刊名: Journal of the American Academy of Dermatology, 2009, Vol.63 (6), pp.1052-1057
来源数据库: Elsevier Journal
DOI: 10.1016/j.jaad.2009.12.017
关键词: vascular malformationvascular tumorWilms tumor 1
英文摘要: Background(#br)Vascular tumors and malformations can be challenging to diagnose. Although they may initially appear very similar, they have distinct clinical courses and management. Wilms tumor 1 (WT1) gene expression has been reported in many different tumors including hematologic malignancies and some solid tumors.(#br)Objective(#br)We sought to evaluate the expression of WT1 in 126 vascular lesions (64 vascular tumors, one Masson tumor, and 61 vascular malformations).(#br)Methods(#br)Based on the International Society for the Study of Vascular Anomalies classification of vascular anomalies, we studied the expression of WT1 in vascular tumors composed of infantile hemangioma, congenital hemangiomas (non-involuting, rapidly involuting, and not otherwise specified), pyogenic granuloma,...
全文获取路径: Elsevier  (合作)
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关键词翻译
关键词翻译
  • vascular 维管的
  • expression 表示
  • tumor 肿胀