European surveillance on Creutzfeldt-Jakob disease
作者: Inga ZerrJean-Philippe BrandelCarlo MasulloDorothee WientjensRajith de SilvaMartin ZeidlerEnrico GranieriSimone SampaoloCornelia van DuijnNicole Delasnerie-LauprêtreRobert WillSigrid Poser
作者单位: 1Department of Neurology, Georg-August University Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany
2U 360 INSERM, Hôpital de la Salpetrière, Paris, France
3Department of Neurology, Catholic University of Sacred Heart, Rome, Italy
4Department of Epidemiology & Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands
5CJD Surveillance Unit, Western General Hospital, Edinburgh, UK
6Department of Neurology, University of Ferrara, Ferrara, Italy
7Department of Neurological Sciences, Second University, Napoli, Italy
刊名: Journal of Clinical Epidemiology, 2000, Vol.53 (7), pp.747-754
来源数据库: Elsevier Journal
DOI: 10.1016/S0895-4356(99)00207-3
关键词: CJDTSERisk factorEpidemiologyTransmissionIatrogenic
原始语种摘要: Abstract(#br)Medical risk factors for Creutzfeldt-Jakob disease (CJD) were analyzed in a prospective ongoing case-control study based on European CJD surveillance. Detailed data on past and recent medical history were analyzed in 405 cases and controls matched by sex, age, and hospital. Data were correlated with polymorphism at codon 129 of the prion protein gene. Our analysis did not support a number of previously reported associations and failed to identify any common medical risk factor for CJD. Although not statistically significant, brain surgery was associated with an increased risk of CJD. A detailed medical history should be obtained in every suspected CJD case in order to identify iatrogenic sources of CJD.
全文获取路径: Elsevier  (合作)
影响因子:5.332 (2012)

  • surveillance 监视
  • matched 匹配的
  • factor 因素
  • European 欧洲人
  • significant 有效的
  • common 普通
  • identify 视为同一
  • correlated 相关
  • statistically 统计地
  • history 历史