Determination of caffeine and identification of undeclared substances in dietary supplements and caffeine dietary exposure assessment
作者: Diana Brito da Justa NevesEloisa Dutra Caldas
作者单位: 1National Institute of Criminalistics, Federal Police Department, 70610-200 Brasilia, DF, Brazil
2Laboratory of Toxicology, Department of Pharmacy, University of Brasília, 70910-900 Brasilia, DF, Brazil
刊名: Food and Chemical Toxicology, 2017, Vol.105
来源数据库: Elsevier Journal
DOI: 10.1016/j.fct.2017.03.063
关键词: Dietary supplementsCaffeineGC/MSUndeclared drugsCaffeine dietary intake
原始语种摘要: Abstract(#br)Caffeine is one of the most consumed stimulants in the world, and is a frequent ingredient of dietary supplements. The aims of this work were to validate a GC-MS method for the quantitation of caffeine and identification of other substances in supplements, mainly weight loss products, and to estimate the caffeine intake by consumers. Sample preparation included extraction with chloroform:water in ultrasonic bath, centrifugation and analysis of the organic layer for caffeine quantitation, and extraction with methanol for identification of other substances. A total of 213 samples of 52 supplement products not registered in Brazil and seized by the Brazilian Federal Police were analyzed. From the 109 samples that declared the amount of caffeine present, 26.6% contained more than...
全文获取路径: Elsevier  (合作)
影响因子:3.01 (2012)

  • caffeine 咖啡碱
  • assessment 评价
  • dietary 饮食的
  • undeclared 未向海关申报的
  • identification 辨认
  • exposure 暴露