Composición de la microbiota intestinal en pacientes con esclerosis múltiple. Influencia del tratamiento con interferón<ce:hsp sp="0.25"/>β-1b
作者: F. Castillo-ÁlvarezP. Pérez-MatuteJ.A. OteoM.E. Marzo-Sola
作者单位: 1Servicio de Neurología, Hospital San Pedro, Logroño, La Rioja, España
2Servicio de Enfermedades Infecciosas, CIBIR-Hospital San Pedro, Logroño, La Rioja, Spain
刊名: Neurología, 2018
来源数据库: Elsevier Journal
DOI: 10.1016/j.nrl.2018.04.006
关键词: MicrobiotaMicrobiomeMetagenomicsDysbiosisPrevotella
原始语种摘要: Abstract(#br)Introduction(#br)The association between gut microbiota and animal models of multiple sclerosis has been well established; however, studies in humans are scarce.(#br)Methods(#br)We performed a descriptive, cross-sectional study comparing the relative composition of gut microbiota in 30 patients with multiple sclerosis (15 treated with interferon β–1b, 15 not receiving this treatment) and 14 healthy controls using next generation sequencing.(#br)Results(#br)Patients with multiple sclerosis and controls showed differences in the proportion of Euryarchaeota , Firmicutes , Proteobacteria , Actinobacteria , and Lentisphaerae phyla and in 17 bacterial species. More specifically, we found significant differences in the proportion of Firmicutes , Actinobacteria , and Lentisphaerae...
全文获取路径: Elsevier  (合作)
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影响因子:1.322 (2012)

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关键词翻译
关键词翻译
  • microbiota 微生物区系
  • intestinal 肠的
  • control 控制
  • mayor 市长
  • transversal 横的