Ultrasensitive label-free photoelectrochemical immunosensor for the detection of amyloid β-protein based on Zn:SnO 2 /SnS 2 -Au nanocomposites
基于Zn:SnO 2/sns2-Au纳米复合材料的超灵敏无标记光电化学免疫传感器检测β-淀粉样蛋白
作者: Ning GaoYifeng ZhangKeke GaoJiandong XieLei LiuYuyang LiLiping QiuQin WeiHongmin MaXuehui Pang
作者单位: 1Collaborative Innovation Center for Green Chemical Manufacturing and Accurate Detection, School of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, PR China
2MOE Key Laboratory of Resources and Environmental System Optimization, College of Environmental Science and Engineering, North China Electric Power University, Beijing, 102206, PR China
3College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan, Shandong, 250014, PR China
4Shandong Jianzhu University, Jinan, Shandong, 250101, PR China
5State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Changsha, 410082, PR China
刊名: Sensors and Actuators: B. Chemical, 2020, Vol.308
来源数据库: Elsevier Journal
DOI: 10.1016/j.snb.2019.127576
关键词: Label-freePhotoelectrochemical immunosensorZn:SnO 2 /SnS 2 -Au nanocompositesAlzheimer’s diseaseAmyloid β-protein
原始语种摘要: Abstract(#br)In this work, an ultrasensitive label-free photoelectrochemical (PEC) immunosensor was designed for the detection of amyloid β-protein (Aβ). Specifically, Zn:SnO 2 /SnS 2 nanocomposites were successfully synthesized by a simple one-pot hydrothermal method and used to build the immunosensor. The combination of SnS 2 and SnO 2 with matching energy levels promoted the layer-by-layer transfer of photogenerated charges, reduced the recombination efficiency of photogenerated electron, and enhanced the photoelectric conversion efficiency. Meanwhile, the addition of Zn ions introduced a trap level, which hindered the reduction of electrons, and the recombination of electron-hole pairs, improved the photocurrent response significantly. On the other hand, Au nanoparticles (NPs) were...
全文获取路径: Elsevier  (合作)
影响因子:3.535 (2012)

  • 改进 选择性
  • immunosensor 免疫感受器
  • label 标签标记
  • protein 蛋白质
  • detection 探测
  • amyloid 淀粉状朊
  • photocurrent 光电流
  • matching 匹配
  • hydrothermal 热液的
  • selectivity 选择性
  • improved 选择性