Interhermispheric inhibition predicts anxiety levels in multiple sclerosis: A corticospinal excitability study
作者: Moussa A. ChalahUlrich PalmJean-Pascal LefaucheurAlain CréangeSamar S. Ayache
作者单位: 1EA 4391, Excitabilité Nerveuse et Thérapeutique, Université Paris-Est-Créteil, Créteil, France
2Service de Physiologie - Explorations Fonctionnelles, Hôpital Henri Mondor, Assistance Publique - Hôpitaux de Paris, Créteil, France
3Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Nussbaumstr, 7, 80336, Munich, Germany
4Service de Neurologie, Hôpital Henri Mondor, Assistance Publique - Hôpitaux de Paris, Créteil, France
5Neurology Division, Lebanese American University Medical Center Rizk Hospital, Beirut, Lebanon
刊名: Brain Research, 2018
来源数据库: Elsevier Journal
DOI: 10.1016/j.brainres.2018.08.029
关键词: Cortical excitabilityTranscranial magnetic stimulationInterhemispheric inhibitionHospital anxiety and depression scaleAnxietyDepression
英文摘要: Abstract(#br)Background(#br)Depression and anxiety stand among the most frequent and debilitating complaints in multiple sclerosis (MS) patients. Understanding their neurophysiological correlates might improve their management. To date, no single study has addressed this issue.(#br)Method(#br)Patients completed the Hospital Anxiety and Depression Scale (HADS). Transcranial magnetic stimulation (TMS) was performed to obtain the following corticospinal excitability measures: resting motor threshold, short interval intracortical inhibition and facilitation, cortical silent period and interhemispheric inhibition. Anxiety and depression scores were the primary outcomes in the univariate analysis. When obtaining significant associations between anxiety/depression and TMS measures, a...
全文获取路径: Elsevier  (合作)
影响因子:2.879 (2012)

  • excitability 兴奋性
  • corticospinal 脊髓皮质的
  • sclerosis 硬化
  • inhibition 抑制
  • stimulation 激励
  • anxiety 忧虑
  • depression 低地
  • multiple 多次的
  • Depression 低气压
  • scale 度盘