Calcium binding protein containing neurons in the gliotic mouse hippocampus with special reference to their afferents from the medial septum and the entorhinal cortex
作者: F.R. TangS.C. ChiaF.L. JiangD.L. MaP.M. ChenY.C. Tang
作者单位: 1Epilepsy Research Laboratory, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433
2Department of Anatomy, National University of Singapore, Singapore
3Neuroscience Research Center, School of Medicine, Xi’an Jiaotong University, Xi’an, PR China
4Department of Biochemistry, Institute of Clinical Research, China–Japan Friendship Hospital, Beijing, PR China
刊名: Neuroscience, 2006, Vol.140 (4), pp.1467-1479
来源数据库: Elsevier Journal
DOI: 10.1016/j.neuroscience.2006.03.022
关键词: CA1dentate gyruspilocarpinestatus epilepticusBrdUneurogenesis
原始语种摘要: Abstract(#br)In CA1 area and the hilus of the dentate gyrus of the mouse hippocampus, drastic reduction of NeuN, calbindin, calretinin, or parvalbumin immunopositive neurons was shown at 3, 7 and 60 days after pilocarpine-induced status epilepticus. In gliotic CA1 area at 60 days, few dendritic branches of calcium binding protein immunopositive neurons could be found suggesting reorganization of the afferents of surviving calcium binding protein immunopositive neurons. Calbindin, calretinin, or parvalbumin and 5-bromo-2′-deoxyuridine (BrdU) double labeling showed that calcium binding protein immunopositive neurons in gliotic CA1 area at 60 days were surviving instead of newly generated neurons. Iontophoretic injection of Phaseolus vulgaris leucoagglutinin into the medial septum and the...
全文获取路径: Elsevier  (合作)
影响因子:3.122 (2012)

  • hippocampus 训马场
  • protein 蛋白质
  • pilocarpine 匹鲁卡品
  • septum 隔壁
  • binding 装订
  • medial 中间的
  • cortex 皮层
  • dentate 锯齿状的
  • gyrus 脑回
  • surviving 存活