Lipid-lowering effect of preoperative statin therapy on postoperative major adverse cardiac events after coronary artery bypass surgery
作者: Matthias ThielmannMarkus NeuhäuserAnja MarrBeate R. JaegerDaniel WendtBernd SchuetzeMarkus KamlerParwis MassoudyRaimund ErbelHeinz Jakob
作者单位: 1Department of Thoracic and Cardiovascular Surgery, West German Heart Center Essen, University Hospital Essen, Essen, Germany
2Department of Cardiology, West German Heart Center Essen, University Hospital Essen, Essen, Germany
3Institute for Medical Informatics, Biometry, and Epidemiology, University Hospital Essen, Essen, Germany.
刊名: The Journal of Thoracic and Cardiovascular Surgery, 2007, Vol.134 (5), pp.1143-1149
来源数据库: Elsevier Journal
DOI: 10.1016/j.jtcvs.2007.07.029
原始语种摘要: Objective(#br)Statins are powerful lipid-lowering drugs that have been proved effective in the prevention of coronary artery disease, clearly reducing the risk of mortality and cardiovascular events. Whether hyperlipidemic patients undergoing coronary artery bypass grafting profit from the lipid-lowering beneficial effects of statins is as yet uncertain. We sought to determine whether preoperative statin therapy may have an effect on outcome among hyperlipidemic patients undergoing coronary artery bypass grafting.(#br)Methods(#br)From January 2000 through March 2006, prospectively recorded clinical data from 3346 consecutive patients undergoing isolated first-time elective coronary artery bypass grafting were analyzed for major adverse cardiac events and all-cause in-hospital mortality....
全文获取路径: Elsevier  (合作)
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关键词翻译
关键词翻译
  • events 定时
  • preoperative 操作前的
  • adverse 逆的
  • coronary 冠状的
  • bypass 旁路
  • artery 动脉
  • cardiac 贲门
  • major 知的
  • hyperlipidemia 高指质血症
  • lowering 降低