Ki-67 grading of nonfunctioning pancreatic neuroendocrine tumors on histologic samples obtained by EUS-guided fine-needle tissue acquisition: a prospective study
作者: Alberto LarghiGabriele CapursoAntonella CarnuccioRiccardo RicciSergio AlfieriDomenico GalassoFrancesca LugliAntonio BianchiFrancesco PanzutoLaura De MarinisMassimo FalconiGianfranco Delle FaveGiovanni Battista DogliettoGuido CostamagnaGuido Rindi
作者单位: 1Digestive Endoscopy Unit, Catholic University, Rome, Italy
2Division of Digestive and Liver Disease, University La Sapienza, Rome, Italy
3Institute of Pathology, Catholic University, Rome, Italy
4Division of Digestive Surgery, Catholic University, Rome, Italy
5Division of Endocrinology, Catholic University, Rome, Italy
6Department of Surgery, University of Verona, Verona, Italy
刊名: Gastrointestinal Endoscopy, 2012, Vol.76 (3), pp.570-577
来源数据库: Elsevier Journal
DOI: 10.1016/j.gie.2012.04.477
原始语种摘要: Background(#br)Preoperative determination of Ki-67 expression, an important prognostic factor for grading nonfunctioning pancreatic endocrine tumors (NF-PETs), remains an important clinical challenge.(#br)Objective(#br)To prospectively evaluate the feasibility, yield, and clinical impact of EUS-guided fine-needle tissue acquisition (EUS-FNTA) with a large-gauge needle to obtain tissue samples for histologic diagnosis and Ki-67 analysis in patients with suspected NF-PETs.(#br)Design(#br)Prospective cohort study.(#br)Setting(#br)Tertiary-care academic medical center.(#br)Patients(#br)Consecutive patients with a single pancreatic lesion suspicious for NF-PET on imaging.(#br)Intervention(#br)EUS-FNTA with a 19-gauge needle.(#br)Main Outcome Measurements(#br)Feasibility and yield of EUS-FNTA...
全文获取路径: Elsevier  (合作)
影响因子:5.21 (2012)

  • neuroendocrine 神经内分泌的
  • pancreatic 胰的
  • histologic 组织的
  • grading 粒级成层
  • needle 针叶
  • guided 制导的
  • gauge 测定
  • determination 测定
  • tissue 组织
  • prospective 远景