Salvage chemotherapy with taxane and platinum for women with recurrent uterine carcinosarcoma
作者: Koji MatsuoMalcolm S. RossMayu YunokawaMarian S. JohnsonHiroko MachidaKohei OmatsuMerieme M. KlobocistaDwight D. ImShinya SatohTsukasa BabaYuji IkedaStephen H. BushKosei HasegawaErin A. BlakeMunetaka TakekumaMasako ShidaMasato NishimuraSosuke AdachiTanja PejovicSatoshi TakeuchiTakuhei YokoyamaYutaka UedaKeita IwasakiTakahito M. MiyakeShiori YanaiTadayoshi NaganoTadao TakanoMian M.K. ShahzadFrederick R. UelandJoseph L. KelleyLynda D. Roman
作者单位: 1Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Southern California, CA, USA
2Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh, PA, USA
3Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan
4Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, KY, USA
5Department of Gynecology, Cancer Institute Hospital, Tokyo, Japan
6Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Albert Einstein College of Medicine, Montefiore Medical Center, NY, USA
7The Gynecologic Oncology Center, Mercy Medical Center, Baltimore, MD, USA
8Department of Obstetrics and Gynecology, Tottori University, Tottori, Japan
9Department of Obstetrics and Gynecology, Kyoto University, Kyoto, Japan
10Department of Obstetrics and Gynecology, The University of Tokyo, Tokyo, Japan
11Division of Gynecologic Oncology, Department of Obstet
刊名: Gynecologic Oncology, 2017, Vol.147 (3), pp.565-571
来源数据库: Elsevier Journal
DOI: 10.1016/j.ygyno.2017.10.008
关键词: Uterine carcinosarcomaRecurrenceChemotherapyTaxanePlatinumSurvival outcome
英文摘要: Abstract(#br)Objective(#br)To examine survival after recurrence (SAR) among women with recurrent uterine carcinosarcoma who received a taxane/platinum doublet as the first-line salvage chemotherapy.(#br)Methods(#br)We retrospectively examined 148 women with recurrent uterine carcinosarcoma who received salvage chemotherapy within a cohort of 906 uterine carcinosarcomas. An independent association of salvage chemotherapy type and SAR was examined with multivariate analysis.(#br)Results(#br)There were 71 (48.0%) women who received a taxane/platinum regimen. On univariate analysis, women who received a taxane/platinum doublet had a higher 2-year SAR rate compared to women who received non-taxane/platinum regimens (55.5% versus 34.8%, P <0.001). On...
全文获取路径: Elsevier  (合作)
分享到:
来源刊物:
影响因子:3.929 (2012)

×
关键词翻译
关键词翻译
  • carcinosarcoma 癌肉瘤
  • chemotherapy 化学疗法
  • uterine 子宫的
  • platinum 
  • recurrent 循环的
  • women 妇女
  • outcome 效果