Enhanced Laws textures: A potential MRI surrogate marker of hepatic fibrosis in a murine model
作者: Baojun LiHernan JaraHeishun YuMichael O'BrienJorge SotoStephan W. Anderson
作者单位: 1Department of Radiology, Boston University School of Medicine, Boston, MA 02118, USA
2Department of Radiology, Masschusetts General Hospital, Boston, MA 02118, USA
3Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA
刊名: Magnetic Resonance Imaging, 2017, Vol.37 , pp.33-40
来源数据库: Elsevier Journal
DOI: 10.1016/j.mri.2016.11.008
关键词: Laws texture featuresT 2ADCLiverFibrosis
英文摘要: Abstract(#br)Purpose(#br)To compare enhanced Laws textures derived from parametric proton density (PD) maps to other MRI surrogate markers (T 2 , PD, apparent diffusion coefficient (ADC)) in assessing degrees of liver fibrosis in an ex vivo murine model of hepatic fibrosis imaged using 11.7T MRI.(#br)Methods(#br)This animal study was IACUC approved. Fourteen male, C57BL/6 mice were divided into control and experimental groups. The latter were fed a 3,5-dicarbethoxy-1,4-dihydrocollidine (DDC) supplemented diet to induce hepatic fibrosis. Ex vivo liver specimens were imaged using an 11.7T scanner, from which the parametric PD, T 2 , and ADC maps were generated from spin-echo pulsed field gradient and multi-echo spin-echo acquisitions. A sequential enhanced Laws texture analysis was applied...
全文获取路径: Elsevier  (合作)
影响因子:2.06 (2012)

  • texture 结构
  • features 特征
  • model 模型
  • potential 
  • fibrosis 纤维化
  • surrogate 代替
  • murine 鼠灰色
  • marker 标试器
  • hepatic 肝的
  • MRI Machine-Readable Information