Relationship between clinical and neuropsychological characteristics in child and adolescent first degree relatives of subjects with schizophrenia
作者: Elena de la SernaInmaculada BaezaJosep ToroSusana AndrésOlga PuigVanessa Sánchez-GuistauSoledad RomeroMiguel BernardoJosefina Castro-Fornieles
作者单位: 1Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Spain
2Department of Child and Adolescent Psychiatry and Psychology, Institut Clinic de Neurociències, Hospital Clínic Universitari, Barcelona, Spain
3Programa Esquizofrenia Clinic, Spain
4Department of Psychiatry, Institut Clínic de Neurociències, Hospital Clínic Universitari, Barcelona, Spain
5Institut d´Investigació Biomèdica August Pi i Sunyer, IDIBAPS, Barcelona, Spain
6Department of Psychiatry and Clinical Psychobiology, Health Sciences Division, University of Barcelona, Spain
刊名: Schizophrenia Research, 2009, Vol.116 (2), pp.159-167
来源数据库: Elsevier Journal
DOI: 10.1016/j.schres.2009.09.001
关键词: High riskChildrenAdolescentNeuropsychologySchizophrenia
原始语种摘要: Abstract(#br)Introduction(#br)Studies have shown higher rates of psychopathology and cognitive difficulties among relatives of schizophrenia patients than among the general population. This study aimed to analyze the relationship between clinical and neuropsychological characteristics in children and adolescents at high genetic risk for schizophrenia.(#br)Methods(#br)Participants were 26 children and adolescent first-degree relatives of subjects diagnosed with schizophrenia (high-risk [HR] group) and 20 controls whose parents and siblings did not meet DSM-IV criteria for any psychotic disorder. These two groups were matched by age, sex and socio-economic status and clinical and neuropsychological assessments were completed by all participants.(#br)Results(#br)Among HR children 42.3% were...
全文获取路径: Elsevier  (合作)
影响因子:4.59 (2012)

  • schizophrenia 精神分裂症
  • relatives 相对数
  • premorbid 临证前期的
  • hyperactivity 过兴奋
  • controls 控制机构
  • between 在中间
  • psychotic 精神病患者
  • adolescent 青年
  • disorder 无序
  • first 第一