Detection of mucosal abnormalities in patients with oral cancer using a photodynamic technique: A pilot study
作者: Martin O’DwyerAdam DayMiles PadgettG.R. OgdenS. McLarenCarol R. Goodman
作者单位: 1Department of Physics and Astronomy, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
2Oral & Maxillofacial Surgery Unit, Unit of Oral Surgery & Medicine, University of Dundee Dental Hospital & School, Park Place, Dundee DD1 4HR, UK
3Scottish PDT Centre, Ninewells Hospital and Medical School, UK
刊名: British Journal of Oral & Maxillofacial Surgery, 2007, Vol.46 (1), pp.6-10
来源数据库: Elsevier Journal
DOI: 10.1016/j.bjoms.2007.05.009
关键词: Photodynamic detectionOral cancerBiopsy
原始语种摘要: Abstract(#br)Patients who have had one oral cancer are at increased risk of developing a further malignant tumour, the detection of which is made difficult (and is often delayed) by the innocuous appearance of the early oral lesion. A technique that could reliably detect early cancers would be useful to both oral and dental health specialists. We describe a pilot study in which we used a compact spectroscopic instrument designed to excite and measure fluorescence in the oral cavity. The data were processed using principal components analysis, and the results suggest that the technique might be valuable for detecting early oral cancers. Further work should be performed to investigate some unusual characteristics observed within our data to ascertain if these are significant, simply due to...
全文获取路径: Elsevier  (合作)

  • detect 探测
  • technique 技术
  • observed 观察到的
  • investigate 
  • early 
  • pilot 驾驶员
  • cancer 癌症
  • principal 屋架
  • might 能力
  • further 进一步