A convenient and highly regio and stereoselective method for the synthesis of ( E )-3-alkylidene isobenzofuran-1(3 H )-ones (phthalides)
作者: Rupa MukhopadhyayNitya G Kundu
作者单位: 1Department of Organic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Calcutta 700 032, India
刊名: Tetrahedron, 2001, Vol.57 (46), pp.9475-9480
来源数据库: Elsevier Journal
DOI: 10.1016/S0040-4020(01)00943-7
关键词: alkynesisobenzofuran-1(3 H )onespalladium catalysis
原始语种摘要: Abstract(#br)2-Iodobenzyl alcohol on treatment with acetylenic carbinols in the presence of a palladium catalyst and copper(I) iodide as a co-catalyst afforded disubstituted alkynes. Jones oxidation of the disubstituted alkynes led to ( E )-3-alkylidene isobenzofuran-1(3 H )-ones in good yields in a highly regio and stereoselective manner. The E -isomers were obtained exclusively instead of the more stable Z -isomers.
全文获取路径: Elsevier  (合作)
影响因子:2.803 (2012)

  • alkylidene 次烷基
  • ones 任何人的
  • phthalides 苯酞
  • regio 
  • convenient 方便的
  • disubstituted 二基取代的
  • isomers 等比值线
  • catalyst 催化剂
  • palladium 
  • highly 高度地