Paving the Way to Personalized Medicine: Production of Some Promising Theragnostic Radionuclides at Brookhaven National Laboratory
作者: Suresh C. Srivastava
作者单位: 1Medical Isotope Research and Production Program, Brookhaven National Laboratory, Upton, NY
刊名: Seminars in Nuclear Medicine, 2012, Vol.42 (3), pp.151-163
来源数据库: Elsevier Journal
DOI: 10.1053/j.semnuclmed.2011.12.004
原始语种摘要: This article reintroduces and reinforces our proposed paradigm that involves specific individual “dual-purpose” radionuclides or radionuclide pairs with emissions suitable for both imaging and therapy and which, when molecularly (selectively) targeted using appropriate carriers, would allow pretherapy low-dose imaging as well as higher-dose therapy in the same patient. We have made an attempt to sort out and organize a number of such theragnostic radionuclides and radionuclide pairs that may thus potentially bring us closer to the age-long dream of personalized medicine for performing tailored low-dose molecular imaging (single-photon emission computed tomography/computed tomography or positron emission tomography/CT) to provide the necessary pretherapy information on biodistribution,...
全文获取路径: Elsevier  (合作)
影响因子:3.818 (2012)

  • National 国民牌大客车
  • organize 
  • great 大的
  • radionuclide 放射性核素
  • purpose 目的
  • provide 规定
  • majority 多数
  • addressed 收信地址
  • information 报告
  • necessary 必要的