Disparities in Perioperative Radiotherapy Use in Elderly Patients with Soft-Tissue Sarcoma
作者: Sriram VenigallaRuben CarmonaNoam VanderWaldeRonnie SebroSonam SharmaCharles B. SimoneRobert J. WilsonKristy L. WeberJacob E. Shabason
作者单位: 1Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
2Department of Radiation Oncology, University of Tennessee Health Science Center-West Cancer Center, Memphis, Tennessee, USA
3Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
4Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
5Department of Radiation Oncology, Mount Sinai School of Medicine, New York, New York, USA
6Department of Radiation Oncology, University of Maryland Medical Center, Baltimore, Maryland, USA
刊名: International Journal of Radiation Oncology, Biology, Physics, 2018
来源数据库: Elsevier Journal
DOI: 10.1016/j.ijrobp.2018.05.019
关键词: Elderly patientsSoft Tissue SarcomaRadiation TherapyCohort StudyHealthcare Disparities
英文摘要: Abstract(#br)Background(#br)The benefit of perioperative radiotherapy in elderly patients with soft tissue sarcoma (STS) is unclear due to their underrepresentation in clinical trials. We assessed patterns-of-care and overall survival (OS) associated with perioperative radiotherapy use in this population.(#br)Patients and Methods(#br)Elderly (≥ 70 years) patients with high grade STS who underwent surgery with or without perioperative radiotherapy from 2004–2013 were identified from the National Cancer Database. A non-elderly cohort (< 70 years) was also identified for secondary comparative analyses. The association between perioperative radiotherapy use and OS was assessed using propensity score-weighted Cox proportional hazards analyses. Relative survival was calculated using national...
全文获取路径: Elsevier  (合作)