Staphylococcus aureus colonization and acquisition of skin and soft tissue infection among Royal Marines recruits: a prospective cohort study
作者: E. JauneikaiteT. FergusonM. MosavieJ.L. FallowfieldT. DaveyN. ThorpeA. AllsoppA.M. ShawD. FudgeM.K. O'SheaD. WilsonM. MorganB. PichonA.M. KearnsS. SriskandanL.E. Lamb
作者单位: 1Department of Medicine, Imperial College London, London, UK
2NIHR Health Protection Research Unit in Antimicrobial Resistance and Healthcare-associated Infections, Imperial College London, London, UK
3Department of Infectious Disease Epidemiology, Imperial College London, London, UK
4Institute of Naval Medicine, Alverstoke, UK
5Department of Microbiology, Royal Devon and Exeter Hospital, Exeter, UK
6Healthcare Associated Infections and Antimicrobial Resistance Division, National Infection Service, Public Health England, London, UK
7Academic Department of Military Medicine, Royal Centre for Defence Medicine (Research and Academia), Birmingham, UK
8Royal Free London NHS Foundation Trust, London, UK
9Institute of Microbiology and Infection, The University of Birmingham, Birmingham, UK
刊名: Clinical Microbiology and Infection, 2020, Vol.26 (3), pp.381.e1-381.e6
来源数据库: Elsevier Journal
DOI: 10.1016/j.cmi.2019.07.014
关键词: Methicillin-resistant S. aureusPanton–Valentine leucocidinRoyal MarinesSkin and soft tissue infectionsStaphylococcus aureus
原始语种摘要: Abstract(#br)Objectives(#br)Skin and soft tissue infections (SSTIs) are a serious health issue for military personnel. Of particular importance are those caused by methicillin-resistant Staphylococcus aureus and Panton–Valentine leucocidin (PVL)-positive S. aureus (PVL-SA), as they have been associated with outbreaks of SSTIs. A prospective observational study was conducted in Royal Marine (RM) recruits to investigate the prevalence of PVL-SA carriage and any association with SSTIs.(#br)Methods(#br)A total of 1012 RM recruits were followed through a 32-week training programme, with nose and throat swabs obtained at weeks 1, 6, 15 and 32. S. aureus isolates were characterized by antibiotic susceptibility testing, spa typing, presence of mecA/C and PVL genes. Retrospective review of the...
全文获取路径: Elsevier  (合作)

  • cohort 伙伴
  • colonization 集群现象
  • infection 感染
  • prospective 远景
  • tissue 组织
  • acquisition 捕获
  • Royal 皇家的英国的
  • among 在当中
  • study 学习