How motility can enhance mass transfer and absorption in the duodenum: Taking the structure of the villi into account
作者: Yanan ZhangPeng WuRomain JeantetDidier DupontGuillaume DelaplaceXiao Dong ChenJie Xiao
作者单位: 1School of Chemical and Environmental Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, Jiangsu Province 215123, China
2STLO, UMR 1253, INRA, Agrocampus Ouest, 35000 Rennes, France
3Unité Matériaux et Transformations (UMET) – UMR 8207, INRA, Team PIHM, 369 rue Jules Guesde, 59651 Villeneuve d'Ascq, France
刊名: Chemical Engineering Science, 2020, Vol.213
来源数据库: Elsevier Journal
DOI: 10.1016/j.ces.2019.115406
关键词: MotilitySmall intestineVilliMass transfer and absorptionNumerical simulationMoving mesh method
英文摘要: Abstract(#br)Given the complex motility of the intestinal wall featuring villous structure, the mechanisms by which the motility can enhance mass transfer and absorption in the small intestine have been a mystery. In this work, the challenging task to couple the intestinal lumen flow and the contraction movement of the villi is tackled by a multi-physics model. The effects of motility of an entire duodenum on the mass transfer and absorption under the influence of ambient flow can be systematically explored. It is revealed that the top of the villi plays a major role in mass absorption. For a rat duodenum, the pendular movement can enhance mass transfer and absorption by up to about 72%. With the introduction of ambient flow, although the absorption amount increases, the enhancement of...
全文获取路径: Elsevier  (合作)
影响因子:2.386 (2012)

  • motility 游动性
  • intestine 
  • duodenum 十二指肠
  • villi 绒毛
  • absorption 吸收
  • transfer 转换
  • simulation 模拟
  • account 计算
  • enhance 增强
  • structure 构造