Experimental Weight Gain Increases Ambulatory Blood Pressure in Healthy Subjects: Implications of Visceral Fat Accumulation
作者: Naima CovassinFatima H. Sert-KuniyoshiPrachi SinghAbel Romero-CorralDiane E. DavisonFrancisco Lopez-JimenezMichael D. JensenVirend K. Somers
作者单位: 1Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN
2Division of Endocrinology, Department of Medicine, Mayo Clinic, Rochester, MN
刊名: Mayo Clinic Proceedings, 2018, Vol.93 (5), pp.618-626
来源数据库: Elsevier Journal
DOI: 10.1016/j.mayocp.2017.12.012
原始语种摘要: Abstract(#br)Objective(#br)To examine whether experimentally induced weight gain raises ambulatory blood pressure (BP) in healthy subjects and identify any relationship between changes in BP and changes in regional fat distribution.(#br)Patients and Methods(#br)Twenty-six normal weight subjects were randomized to 8 weeks of weight gain through overfeeding (n=16; age, 30.4±6.6 years) or to weight maintenance (controls; n=10; age, 27.1±7.7 years) between July 2004 and August 2010. Measures of body composition via dual energy X-ray absorptiometry and computed tomography, circulating biomarkers, and 24-hour ambulatory BP were obtained at baseline and after the 8-week experimental phase.(#br)Results(#br)Overfeeding resulted in 3.7 kg (95% CI, 2.9-4.5) increase in body weight in weight gainers,...
全文获取路径: Elsevier  (合作)
影响因子:5.79 (2012)

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