Preoperative serum ST2 level predicts acute kidney injury after adult cardiac surgery
作者: Kevin W. LobdellDevin M. ParkerDonald S. LikoskyMichael RezaeeMoritz Wyler von BallmoosShama S. AlamSherry OwensHeather Thiessen-PhilbrookTodd MacKenzieJeremiah R. Brown
作者单位: 1Carolinas HealthCare System, Charlotte, NC
2The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine, Lebanon, NH
3Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH
4Institute for Healthcare Policy and Innovation
5Section of Health Services Research and Quality, Department of Cardiac Surgery, University of Michigan, Ann Arbor, Mich
6Section of Urology, Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH
7Division of Cardiovascular and Thoracic Surgery, Duke University Medical Center, Durham, NC
8Program of Applied Translational Research, Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Conn
9Department of Community and Family Medicine, Geisel School of Medicine, Lebanon, NH
刊名: The Journal of Thoracic and Cardiovascular Surgery, 2018
来源数据库: Elsevier Journal
DOI: 10.1016/j.jtcvs.2018.03.149
关键词: Acute kidney injuryST2Cardiac surgeryBiomarkers
英文摘要: Abstract(#br)Objective(#br)The purpose of this study was to evaluate the relationship between preoperative levels of serum soluble ST2 (ST2) and acute kidney injury (AKI) after cardiac surgery. Previous research has shown that biomarkers facilitate the prediction of AKI and other complications after cardiac surgery.(#br)Methods(#br)Preoperative ST2 proteins were measured in 1498 patients undergoing isolated coronary artery bypass graft surgery at 8 hospitals participating in the Northern New England Biomarker Study from 2004 to 2007. AKI severity was defined using the Acute Kidney Injury Network (AKIN) definition. Preoperative ST2 levels were measured using multiplex assays. Ordered logistic regression was used to examine the relationship between ST2 levels and levels of AKI...
全文获取路径: Elsevier  (合作)

  • adult 成体
  • acute 急尖的
  • injury 损害
  • kidney 肾脏
  • serum 血清
  • cardiac 贲门
  • level 水准
  • surgery 外科
  • after 在之后