Perinatal exposure to dioxins and dioxin-like compounds and infant growth and body mass index at seven years: A pooled analysis of three European birth cohorts
作者: Nina IszattHein StigumEva GovartsLubica Palkovicova MurinovaGreet SchoetersTomas TrnovecJuliette LeglerCathrine ThomsenGudrun KoppenMerete Eggesbø
作者单位: 1Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
2VITO, Unit of Environmental Risk and Health, Mol, Belgium
3Slovak Medical University, Faculty of Public Health, Department of Environmental Medicine, Bratislava, Slovakia
4University of Southern Denmark, Department of Environmental Medicine, Odense, Denmark
5University of Antwerp, Department of Biomedical Sciences, Antwerp, Belgium
6VU University Amsterdam, Institute for Environmental Studies, Amsterdam, The Netherlands
7Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo, Norway
刊名: Environment International, 2016, Vol.94 , pp.399-407
来源数据库: Elsevier Journal
DOI: 10.1016/j.envint.2016.04.040
关键词: DioxinsDioxin-like PCBsBirth cohortsInfant growthBMIObesity
英文摘要: Abstract(#br)Background(#br)Dioxins and dioxin-like compounds are endocrine disrupting chemicals (EDCs). Experimental studies suggest perinatal exposure to EDCs results in later obesity. However, the few epidemiological investigations on dioxins are inconclusive. We investigated perinatal exposure to dioxins and dioxin-like compounds, infant growth and body mass index (BMI) in childhood.(#br)Methods(#br)We pooled data from 3 European birth cohorts (Belgian, Norwegian, Slovak) with exposure assessment in cord blood or breast milk. Two cohorts had dioxin-like toxicity assessed using dioxin-responsive chemical-activated luciferase expression (DR-CALUX) bioassay and one cohort had measured concentrations of dioxins, furans and dioxin-like polychlorinated biphenols with CALUX relative potency...
全文获取路径: Elsevier  (合作)
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影响因子:6.248 (2012)

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关键词翻译
关键词翻译
  • growth 生长
  • index 指标
  • Infant 伊洛魁夜间战斗机和夜间跟踪系统
  • seven 
  • European 欧洲人
  • analysis 分析
  • infant 幼儿
  • exposure 暴露
  • compounds 化合物
  • three