The efficacy and safety of sublingual immunotherapy in children and adult patients with allergic rhinitis
作者: X. LinH. LinX. WeiQ. Huang
作者单位: 1Department of Otorhinolaryngology & Head and Neck Surgery, Hainan General Hospital, Haikou 570311, China
2Department of Otorhinolaryngology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China
刊名: Allergologia et Immunopathologia, 2017, Vol.45 (5), pp.457-462
来源数据库: Elsevier Journal
DOI: 10.1016/j.aller.2016.10.016
关键词: Allergic rhinitisSublingual immunotherapyDermatophagoides farinaeEfficacyYoung children
原始语种摘要: Abstract(#br)Background(#br)Clinical research has shown that sublingual immunotherapy (SLIT) is effective and safe in moderate-severe allergic rhinitis (AR) induced by house dust mite (HDM). However, the sample size in many studies is small. Meanwhile, the controversy on the efficacy and safety in the very young children younger than four years old still existed.(#br)Objective(#br)The aim of this retrospective study is to evaluate the efficacy and safety of SLIT with Dermatophagoides farinae ( Der.f ) extracts in children and adult patients with allergic rhinitis, particularly in the very young children.(#br)Method(#br)A total of 573 subjects aged 3–69 with AR received a three-year course of sublingual immunotherapy with Der.f extracts along with pharmacotherapy. The total nasal symptoms...
全文获取路径: Elsevier  (合作)
影响因子:1.229 (2012)

  • rhinitis 鼻炎
  • sublingual 舌下的
  • immunotherapy 免疫疗法
  • allergic 变应性的
  • adult 成体
  • efficacy 效验
  • safety 安全
  • nasal 鼻的
  • extracts 摘记
  • children 子女