Fabrication and biocompatibility of polyethyleneimine/heparin self-assembly coating on NiTi alloy
作者: Ping DongWeichang HaoXu WangTianmin Wang
作者单位: 1Center of Materials Physics and Chemistry, Beihang University, Beijing 100083, China
刊名: Thin Solid Films, 2007, Vol.516 (16), pp.5168-5171
来源数据库: Elsevier Journal
DOI: 10.1016/j.tsf.2007.07.084
关键词: NiTi alloyHeparin sodiumBiocompatibilityLBL
原始语种摘要: Abstract(#br)NiTi alloy has been used widely as biomaterials. But because of toxic effects possibly caused by excess Ni ions released during the corrosion process in the physiological environment, it is still a controversial material. Fabricating medicine-loaded coating, which is expected to decrease the release of Ni ions and improve the biocompatibility of the materials, is a potential way to solve the problem. In this paper, NiTi alloy is coated by polyethyleneimine/heparin films via layer-by-layer (LBL) self-assembly method. UV–Vis, FT-IR, atomic force microscopy (AFM) and contact angle measurements are used to characterize the microstructure of coatings and select the best fabrication conditions. Potentiodynamic polarization researches in sodium chloride and dynamic clotting time...
全文获取路径: Elsevier  (合作)
影响因子:1.604 (2012)

  • heparin 肝素
  • assembly 组装
  • alloy 合金
  • coating 覆盖层
  • sodium 
  • clotting 凝固
  • capability 能力
  • corrosion 腐蚀
  • expected 预期
  • conditions 条件式