Turning omics data into therapeutic insights
作者: Amanda KedaigleErnest Fraenkel
作者单位: 1Computational & Systems Biology Program and the Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
刊名: Current Opinion in Pharmacology, 2018, Vol.42 , pp.95-101
来源数据库: Elsevier Journal
DOI: 10.1016/j.coph.2018.08.006
原始语种摘要: Omics technologies have made it easier and cheaper to evaluate thousands of biological molecules at once. These advances have led to novel therapies approved for use in the clinic, elucidated the mechanisms behind disease-associated mutations, led to increased accuracy in disease subtyping and personalized medicine, and revealed novel uses and treatment regimes for existing drugs through drug repurposing and pharmacology studies. In this review, we summarize some of these milestones and discuss the potential of integrative analyses that combine multiple data types for further advances.
全文获取路径: Elsevier  (合作)
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来源刊物:
影响因子:5.443 (2012)

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关键词翻译
关键词翻译
  • advances 预付款
  • biological 生物学的
  • treatment 处理
  • through 经过
  • behind 在后
  • summarize 概括
  • pharmacology 药理学
  • therapeutic 治疗的
  • potential 
  • approved 认可的