Coumarins as potential supportive medication for the treatment of epilepsy
作者: Jarosław Bryda12 Mirosław Zagaja2 Aleksandra Szewczyk2 and Marta Andres‑Mach2*
作者单位: 1; e-mail: mandres@wp.pl1Department of Veterinary Hygiene
2 Voivodship Veterinary Inspectorate
3 Lublin
4 Poland
52Isobolographic Analysis Laboratory
6 Institute of Rural Health
7
刊名: Acta Neurobiologiae Experimentalis, 2019, Vol.79 (79)
来源数据库: Exeley Inc.
原始语种摘要: Epilepsy, one of the most common neurological disorders, is a chronic disease of the brain manifested by seizures due to sudden, spontaneous bioelectrical discharges in nerve cells. An estimated 50 million people worldwide suffer from epilepsy. Antiepileptic drugs are the mainstream treatment for epilepsy; however, the drug resistance occurring in 20‑30% of patients and side effects of available medications have resulted in a search for natural remedies that can support disease therapy. Coumarins may be a promising option. They are a group of natural plant‑derived substances of great interest due to their broad spectrum of biological activities, including potent pharmacological properties. Recent data from experimental models demonstrates the possibility for coumarin use as a supporting t...
全文获取路径: Exeley 公司  (合作)
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影响因子:1.977 (2012)

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关键词翻译
关键词翻译
  • epilepsy 癫痫
  • supportive 支援性
  • potential 
  • epileptic 癫痫
  • treatment 处理
  • medication 药疗法
  • remedies 救济方法
  • nerve 叶脉
  • worldwide 世界的
  • available 可供应的