Isolation and characterization of human amniotic fluid and SH‑SY5Y/ BE(2)‑M17 cell derived exosomes
作者: Nayer Seyfizadeh12 Narges Seyfizadeh3 Reza Rahbarghazi1 Alireza Nourazarian1 Sajed Borzouisileh4 Abdolhakim Palideh5 Farideh Elahimanesh6 Hamed Hamishehkar7 Leyla Salimi1 Mohammad Nouri18 Maryam Abtin9
作者单位: 1; e-mail: seyfizadehn@gmail.com1Stem Cell Research Center
2 Tabriz University of Medical Sciences
3 Tabriz
4 Iran
5 2Department of Biochemistry and Clinical Laboratories
6 Faculty of Medicine
7 3National Center for Tumor Diseases
8 University of Heidelberg
9 Heidelberg
10 Germany
11 4Medical Plants Research Center
12 Yasuj University of Medical Sciences
13 Yasuj
14 5Faculty of Dentistry
15 Babol University of Medical Sciences
16 Babol
17 6Department of Radiology
18 School of Paramedical Science
19 Kurdistan University of Medical Sciences
20 Sanandaj
21 7Drug Applied Research Center
22 8Stem Cell and Regenerative Medicine Institute
23 9Department of Medical Genetics
刊名: Acta Neurobiologiae Experimentalis, 2019, Vol.79 (79)
来源数据库: Exeley Inc.
原始语种摘要: The application of stem cells as a therapy for degenerative disease holds great promise. Substantial evidence suggests that stem cell derived exosomes are a novel cell‑free therapy for the corresponding cells. Exosomes are less complex as compared to their parental cells, due to the fewer number of membrane proteins. In addition, the smaller size and lower risk of immunogenicity makes exosomes potentially safe therapeutic nano‑carriers. A large number of ongoing research studies are focused on characterizing exosomes that were derived from different sources, for their potential use in various therapeutic applications. In the present study, we focused on characterizing human amniotic fluid stem cell derived exosomes for future therapeutic applications, such as paracrine therapy/nano...
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影响因子:1.977 (2012)

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关键词翻译
关键词翻译
  • BE Belgium
  • derived 导生的
  • amniotic 羊膜的
  • addition 添加
  • fluid 
  • therapeutic 治疗的
  • various 千变万化的
  • potentially 可能地
  • immunogenicity 致免疫性
  • human 人的