Tumor cell vanishing with radiological changes suggesting progression in IDH-mutated diffuse astrocytoma treated only with surgery
作者: Aurelio Hernandez-LainAmaya HilarioJuan Manuel SepulvedaDiana CanteroAna RamosAngel Perez-Nuñez
刊名: Clinical Neuropathology, 2018, Vol.37 (5), pp.217-220
来源数据库: Dustri-Verlag Dr. Karl Feistle GmbH & Co. KG
DOI: 10.5414/NP301116
原始语种摘要: The radiological diagnosis of glioma progression is still challenging. A 33-year-old woman diagnosed with a frontal tumor underwent awake craniotomy with total tumor resection. The diagnosis was IDH-mutated diffuse astrocytoma, WHO grade II. The patient did not receive additional radiotherapy or chemotherapy. Periodic MRI scans showed a T2/FLAIR nodular enlargement which appeared de novo and grew slowly and gradually until 4 years post surgery. The patient underwent a second craniotomy to completely resect the T2/FLAIR hyperintensity. In the histological and molecular study of the second resection, no tumor cells were identified. We could hypothesize that the reactive changes favored by surgery could explain the ongoing radiologic findings.
全文获取路径: Dustri出版社 
影响因子:1.341 (2012)

  • astrocytoma 星形细胞瘤
  • diffuse 普及
  • radiological 放射性
  • resection 后方交会
  • vanishing 消失
  • treated 加工的
  • chemotherapy 化学疗法
  • glioma 神经胶质瘤
  • hypothesize 假定
  • progression 级数