Clinical distribution and molecular profiling on postoperative colorectal cancer patients with different traditional Chinese medicine syndromes
作者: Jin Li-JunLiu YingZhang Ming-MingHan Xue-MengLi Qiu-JieXiang YuZhai Bing-TaoChen PengChen Xia-YingWang Wen-GangLiu Shui-PingTing DuanFeng JiaoXie TianSui Xin-Bing
作者单位: 1Department of Traditional Chinese Medicine, Hangzhou Jianggan District People’s Hospital, Hangzhou, China
2;Department of Medical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China
3Holistic Integrative Pharmacy Institutes and Comprehensive Cancer Diagnosis and Treatment Center, the Affiliated Hospital of Hangzhou Normal University, College of Medicine, Hangzhou Normal University, Hangzhou, China
4Key Laboratory of Elemene Class Anti-cancer Chinese Medicine of Zhejiang Province and Engineering Laboratory of Development and Application of Traditional Chinese Medicine from Zhejiang Province, Hangzhou Normal University, Hangzhou, China.
刊名: Traditional Medicine Research, 2020, Vol.5 (1), pp.44-52
来源数据库: TMR publishing group
原始语种摘要: HighlightsThe identification of syndrome conditions had different impacts on CRC prognosis, and which may be related with different mRNA expression levels. Our results prelimitarily uncovered that some oncogenes and pro-inflammatory cytokines were highly expressed in Dampness Heat group but not other syndrome types and CRC patients with Dampness Heat syndrome might have a poor prognosis.(#br)TraditionalityTCM syndrome is a kind of pathological profiles that reflect signs and symptoms at a certain stage of a disease, which is the most essential guidelines for the prescription of Chinese herbal formulae and also an important classification for CRC TCM therapy. A clear understanding biological basis of TCM syndrome will help the clinical diagnosis and the treatment for CRC patients...
全文获取路径: 传统医学研究 

  • prognosis 预报
  • syndrome 症候群
  • TCM Time Compression Multiplex
  • cytokines 细胞浆移动
  • inflammatory 激怒的
  • mRNA m核糖核酸
  • expression 表示
  • postoperative 手术后的
  • medicine 
  • molecular 分子的