The agro-industrial complex (AIC) is a vital sphere of the economy of any region. The agro-industrial complex provides food independence of the subject, forms a raw-material base for other branches, gives workplaces. Thereby, it promotes increase of well-being and a population standard of life, and also development of rural territories. One of the sharpest and actual problems for today is construction of the effective and flexible mechanism of management by economic development of branch complexes as basic skeleton of regions. According to it formation of mechanisms of adjustment of difficult economic systems – agro-industrial regional complexes with a views of their effective adaptation to changes of factors of the external and internal environment, and also within the limits of programs... of import substitution is actual.