In this paper, thermal model consisting of energy-exergy- analysis for variable speed compressor vapour refrigeration system is developed for using ecofriendly refrigerants was developed. The experiments were conducted on the system for several days for variable brine mass flow rates in the secondary circuit of evaporator and water is flowing in the secondary circuit of condenser. The developed model validates experimental results well. The developed model can predict the thermal performances of VCRS along with performance parameters including condenser and evaporator pressures (Bar), condenser and evaporator temperatures, variations in three LMTDs ( because condenser consists of vapour and liquid parts ), Evaporator and condenser loads, work done by the compressors, evaporator and... condenser heat transfer coefficients (w/m2K). This model predicts the similar behaviour for other ecofriendly refrigerants. It is found that the performance of HFO refrigerants is slightly less than HFC (R-134a) refrigerant. The performance of R1234ze is higher than R1234yf but lower than R134a.