The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study
作者: Fatma Hanci Mehmet Canpolat Huseyin PerHakan Gumus Sefer Kumandas
刊名: Experimental Biomedical Research, 2019, Vol.2 (2)
来源数据库: Experimental Biomedical Research Editorial Office
DOI: 10.30714/j-ebr.2019250351
关键词: EpilepsyAntiepileptic drugsCognitive functionsWISC-RChildhood.
原始语种摘要: Aim: This study investigated the effect of antiepileptic drug monotherapy on cognitive functions in pediatric epilepsy patients. Methods: 98 recently diagnosed epilepsy patients aged 6-16 years were included. All patients underwent routine laboratory tests, electroencephalography, brain magnetic resonance imaging, and intelligence testing. The patients were treated with valproic acid (VA), carbamazepine (CBZ), oxcarbazepine (OXC), or levetiracetam (LEV). The Wechsler Intelligence Scale for Children (WISC-R) was applied three times, before, six months and 12 months after the start of antiepileptic therapy. Results: No significant difference was determined among the mean verbal, performance and total intelligence scores of patients using a single antiepileptic drug at baseline, after six or...
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  • antiepileptic 镇痫剂
  • epilepsy 癫痫
  • observational 观察的
  • childhood 幼年
  • carbamazepine 卡马西平
  • cognitive 修]认知[识
  • laboratory 实验室
  • monotherapy 硫化物
  • intelligence 智能
  • prospective 远景